A semi-trailer has hit up to six cars before slamming into a bollard near the intersection of Nudgee road and Airport Drive in Hendra.
The Courier Mail reports that paramedics are treating multiple people at the scene. The Forensic Crash Unit police are also in attendance.
QLD Traffic Brisbane Metro reports that lengthy delays are expected, with police asking motorists to avoid the area.
The Courier says in its report that one person has been taken to Royal Brisbane Hospital for spinal precautions and a shoulder injury.
Follow further Courier Mail coverage here.